Oklahoma vs. Tennessee odds, prediction: 2026 SEC men's college basketball picks from proven model

In this crucial SEC showdown, the Tennessee Volunteers take on the Oklahoma Sooners on Wednesday. Tennessee is coming off a 73-63 win over LSU on Saturday, while Oklahoma defeated Georgia 94-78 that same day. The Volunteers (18-7, 8-4 SEC) have won two in a row and are 13-1 at home this season. The Sooners (13-12, 3-9 SEC) have also won two in a row, and are 2-6 on the road.

Tipoff from the Food City Center in Knoxville, Tennessee, is set for 7 p.m. ET. Tennessee leads the all-time series 2-0. Tennessee is a 10.5-point favorite in the latest Oklahoma vs. Tennessee odds from DraftKings Sportsbook, while the over/under for total points scored is 149.5. 

Before making any Oklahoma vs. Tennessee picks, check out the college basketball predictions from the SportsLine Projection Model.

The SportsLine Projection Model simulates every college basketball game 10,000 times and entered Week 16 on a sizzling 11-1 run on top-ranked over/under picks dating back to last year, and is on an 13-7 run on top-rated CBB side picks. Anyone following could have seen HUGE returns!

The model has simulated Oklahoma vs Tennessee 10,000 times and the results are in. The model is leaning Over, and it also says one side of the spread hits well over 60% of the time!

So who wins Oklahoma vs Tennessee, and which side of the spread hits well over 60% of the time? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has simulated this matchup 10,000 times!