Oklahoma vs. Tennessee odds, line: 2025 college football picks for Week 10 predictions from proven model

The No. 18 Oklahoma Sooners (6-2) and the No. 14 Tennessee Volunteers (6-2) link up in an SEC showdown on Saturday afternoon. The Sooners are coming off a 34-26 loss to Ole Miss. As for Tennessee, they blew out Kentucky 56-34. 

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Kickoff from the Neyland Stadium in Knoxville, Tennessee, is at 7:30 p.m. ET. The Volunteers are 2.5-point favorites in the latest Oklahoma vs. Tennessee odds, while the over/under for total points scored is 55.5 via SportsLine consensus. 

Before making any Oklahoma vs. Tennessee picks, be sure to check out the college football predictions and betting advice from the SportsLine Projection Model.

The model simulates every FBS game 10,000 times. Since its inception, it has generated a betting profit of over $2,000 for $100 players on its top-rated college spread football picks, and it enters Week 10 on a profitable 47-33 combined run on money-line and over/under picks since the beginning of 2024. Anyone following could have seen impressive returns.

The model has simulated Oklahoma vs. Tennessee 10,000 times and the results are in. We can tell you that the model is leaning under, and it also says one side of the spread is the better value!

So who wins Oklahoma vs. Tennessee, and which side of the spread is the better value? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its college football picks!

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