The Oklahoma State Cowboys will take on the Arizona State Sun Devils at 7:30 p.m. ET on Saturday at Boone Pickens Stadium. The Cowboys are 1-0 overall and 1-0 at home, while ASU is 1-0 overall and 0-0 on the road. Oklahoma State ended last year first in the Big 12, while the Sun Devils ended up second in the Pac-12 South. 

The Cowboys are favored by 11 points in the latest Oklahoma State vs. Arizona State odds from Caesars Sportsbook, and the Over/Under is set at 58. Before you make any Arizona State vs. Oklahoma State picks, you'll want to see the college football predictions from the SportsLine Projection Model.

The SportsLine Projection Model simulates every FBS college football game 10,000 times. Over the past six-plus years, the proprietary computer model has generated a stunning profit of almost $3,500 for $100 players on its top-rated college football picks against the spread. It enters Week 2 of the 2022 college football season on a 48-37 run on all top-rated college football spread and money-line picks that dates back to 2021. Anyone who has followed it has seen HUGE returns.

Now, it has simulated Oklahoma State vs. Arizona State 10,000 times and the results are in. We can tell you that the model is leaning Under, and it's also generated a point-spread pick that is hitting in well over 60% of simulations. You absolutely need to see it before locking in your own picks.

So who wins Oklahoma State vs. Arizona State? And which side of the spread is a must-back? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its college football picks... If you're already a member, see the picks below!