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Ohio vs. UMass odds, line: 2025 college football picks for Week 13 predictions from proven model

SportsLine's model has locked in its best bets for Tuesday's MACtion game featuring Massachusetts vs. Ohio

By@Daniel_LewisSLPublished: Nov 18, 2025 9:10PM UTC . 2 min read

The penultimate slate of midweek MACtion unfolds in Week 13, and one of the Tuesday matchups is the Ohio Bobcats (6-4) against the UMass Minutemen (0-10) on CBS Sports Network. 

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Kickoff is at 7 p.m. ET from Peden Stadium. The Bobcats are 33.5-point favorites in the latest Ohio vs. UMass odds, while the over/under is 53.5.

Before making any UMass vs. Ohio picks, be sure to check out the college football predictions and betting advice from the SportsLine Projection Model.

The model simulates every FBS game 10,000 times, and it is profitable on its top-rated money-line and over/under picks since the beginning of the 2024 season. Anyone following could have seen impressive returns.

The model has simulated UMass vs. Ohio 10,000 times and the results are in. We can tell you that the model is leaning Over, and it also says one side of the spread hits well over 50% of the time!

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