Ohio State vs. Michigan odds, prediction: 2026 Big Ten Conference Tournament men's college basketball picks from proven model

The eighth-seeded Ohio State Buckeyes take on the top-seeded Michigan Wolverines in a Big Ten Conference Tournament quarterfinal on Friday afternoon. Ohio State is coming off a 72-69 win over Iowa on Thursday, while Michigan closed out its regular-season schedule with a 90-80 win over Michigan State on Sunday. The Buckeyes (21-11), who are 2-7 against ranked opponents, have won four in a row. The Wolverines (29-2), who have won four in a row, are looking to win their second consecutive Big Ten Conference Tournament championship.

Tip-off from the United Center in Chicago is set for noon ET. Michigan leads the all-time series 110-84, including a two-game season sweep of the Buckeyes. Michigan is a 12.5-point favorite in the latest Ohio State vs. Michigan odds from DraftKings Sportsbook, while the over/under for total points scored is 154.5. 

Before making any Ohio State vs. Michigan picks, check out the college basketball predictions from the SportsLine Projection Model.

The SportsLine Projection Model simulates every college basketball game 10,000 times. It entered conference tournament week on a sizzling 14-2 run on top-ranked over/under picks dating back to last year, and is on an 28-21 run on top-rated CBB side picks. Anyone following could have seen HUGE returns!

The model has simulated Ohio State vs. Michigan 10,000 times and the results are in. The model is leaning Over, and it also says one side of the spread hits in nearly 70% of simulations!

So who wins Ohio State vs. Michigan, and which side of the spread hits nearly 70% of the time? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has simulated this matchup 10,000 times!