The second round of the ACC Tournament has the No. 12 seed Notre Dame Fighting Irish going up against the No. 5 seed Wake Forest Demon Deacons on Wednesday at 2:30 p.m. ET. The Demon Deacons are 9.5-point favorites in the latest Notre Dame vs. Wake Forest odds via SportsLine consensus, while the over/under for total points scored is 136.5 (see up-to-date odds for every game this week on our college basketball odds page). 

Before making any Notre Dame vs. Wake Forest picks, you need to check out the college basketball predictions from the SportsLine Projection Model.

The model simulates every Division I college basketball game 10,000 times. It enters 2024 conference championship week on a 145-104 roll on all top-rated college basketball picks dating back to last season, returning more than $1,700 for $100 players. It also has a strong 28-18 (+820) record on top-rated spread picks this season. Anyone following has seen HUGE returns!

The model knows Notre Dame freshman guard Markus Burton is an agile ball handler in the backcourt. Burton creates his own shot from all three levels, logging 17.3 points and 4.3 assists per game. He's scored 20-plus points in two straight games. In the first-round win over Georgia Tech, Burton had 21 points and eight assists.

The model also Wake Forest junior guard Hunter Sallis is a creative finisher around the rim and is able to hang in the air. Sallis also has a nice jumper. The Nebraska native led the team in scoring (18.3) with 4.2 rebounds per contest. In his last outing, he racked up 22 points and seven boards.

Now, the model has set its sights on Notre Dame vs. Wake Forest. We can tell you the model is leaning Over on the point total, and it also says one side of the spread hits in well over 50% of simulations! 

Who wins Notre Dame vs. Wake Forest, and which side of the spread hits in well over 50% of simulations? ... Join SportsLine right now to find out which side of the spread you should be all over, all from that's on a 28-18 roll on top-rated college basketball spread picks!