Notre Dame vs. Indiana line, odds: Advanced model reveals college basketball picks, predictions for Dec. 18, 2021

Notre Dame (4-4) and Indiana (8-2) meet up for a contest at the 2021 Crossroads Classic on Saturday afternoon at 2:30 p.m. ET. The Fighting Irish are coming off an upset victory. On Dec. 11, Notre Dame beat No. 21 Kentucky 66-62. Indiana blew out Merrimack 81-49 in its last matchup. Indiana is favored by 4.5 points at Caesers Sportsbook, while the Over-Under is set at 132.5.

Before making any Notre Dame vs. Indiana picks, you NEED to check out the college basketball predictions from the SportsLine Projection Model.  

The SportsLine Projection Model simulates every Division I college basketball game 10,000 times. Over the past five-plus years, the proprietary computer model has generated an impressive profit of over $2,400 for $100 players on its top-rated college basketball picks against the spread. Anyone who has followed it has seen HUGE returns.

The model knows Notre Dame junior guard Dane Goodwin is averaging 14.3 points with 5.5 rebounds per game. The Ohio native has scored at least 10 points in every game this year. In the upset victory against No. 21 Kentucky, Goodwin had 14 points, six rebounds, and shot 5 of 9 from the floor.

The model also knows Indiana junior forward Trayce Jackson-Davis is logging 19.3 points, 8.4 rebounds, and 3.4 blocks. Jackson-Davis has recorded three double-doubles during the season. Against Syracuse, the Indiana native had a monster outing. He had 31 points and 16 rebounds. 

Now, it has set its sights on Notre Dame vs. Indiana. We can tell you the model is leaning over the total and it also says one side of the spread hits in over 50 percent of simulations! You ABSOLUTELY need to see it before locking in any college basketball picks.

Who wins Notre Dame vs. Indiana? And which side of the spread hits in over 50 percent of simulations? ... Join SportsLine right now to find out which side of Notre Dame vs. Indiana spread you should be all over Saturday, all from the model on a roll on college basketball picks!