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Northern Illinois vs. Western Michigan odds, line: 2025 college football picks for Week 13 predictions from proven model

SportsLine's model has locked in its best bets for Tuesday's MACtion game featuring Western Michigan vs. Northern Illinois

ByPublished: Nov 18, 2025 9:20PM UTC . 2 min read

The penultimate week of MACtion begins on Tuesday with three conference games, including Western Michigan visiting Northern Illinois. WMU (6-4, 5-1 MAC) has sole possession of first place in the Mid-American Conference and is coming off a 17-13 win over Ohio. NIU (3-7, 2-4 MAC) is in 11th place of the 13-team conference but has won two of its last three, taking down UMass 45-3 last week. The Huskies have won each of the last three matchups.

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Kickoff is at 7 p.m. ET from Huskie Stadium in Dekalb, Ill. The Broncos are 6.5-point favorites in the latest Northern Illinois vs. Western Michigan odds, while the over/under for total points scored is 38.5 via SportsLine consensus. 

Before making any Western Michigan vs. Northern Illinois picks, be sure to check out the college football predictions and betting advice from the SportsLine Projection Model.

The model simulates every FBS game 10,000 times. Since its inception, it has generated a betting profit of over $2,000 for $100 players on its top-rated college spread football picks. Anyone following could have seen impressive returns.

The model has simulated Northern Illinois vs. Western Michigan 10,000 times and the results are in. We can tell you that the model is leaning Over, and it also says one side of the spread hits well over 70% of the time!

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Ross Kelly
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