The No. 17 North Carolina Tar Heels will try to build on their impressive season-opening performance when they host the Appalachian State Mountaineers on Saturday evening. North Carolina beat South Carolina by two touchdowns in the Duke's Mayo Classic. Appalachian State opened the season with a 45-24 win over Gardner-Webb, narrowly failing to cover the 22.5-point spread. 

Kickoff is set for 5:15 p.m. ET on Saturday at Kenan Memorial Stadium in Chapel Hill. North Carolina is favored by 18 points in the latest North Carolina vs. Appalachian State odds, while the over/under is set at 58 points, per SportsLine consensus. 

Before entering any Appalachian State vs. North Carolina picks, you NEED to see the college football predictions from the model at SportsLine.

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The model has simulated North Carolina vs. Appalachian State 10,000 times and the results are in. We can tell you that the model is leaning Over, and it's also generated a point-spread pick that is hitting in well over 50% of simulations. You can only see the pick at SportsLine.

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