North Carolina Central vs. Penn State odds, prediction: 2025 men's college basketball picks from proven model

Teams looking to get back into the win column meet when the North Carolina Central Eagles battle the Penn State Nittany Lions in non-conference action on Monday afternoon. North Carolina Central is coming off a 74-72 loss to Longwood on Dec. 20, while Penn State is coming off an 80-46 loss at Pittsburgh on Dec. 21. The Eagles (4-10), who have lost four of five, are 0-8 on the road this season. The Nittany Lions (8-4), who have lost three in a row, are 6-1 on their home court in 2025-26.

Tip-off from Bryce Jordan Center in State College, Pa., is set for 1 p.m. ET. This will be the first-ever meeting between the teams. Penn State is a 22.5-point favorite in the latest North Carolina Central vs. Penn State odds from SportsLine consensus, while the over/under for total points scored is 149.5.

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Before making any North Carolina Central vs. Penn State picks, check out the college basketball predictions from the SportsLine Projection Model.

The SportsLine Projection Model simulates every college basketball game 10,000 times and enters Week 8 on a sizzling 7-1 run on top-ranked over/under picks. Anyone following could have seen HUGE returns!

The model has simulated North Carolina Central vs. Penn State 10,000 times and the results are in. We can tell you that the model is leaning Over, and it also says one side of the spread hits in well over 60% of simulations!

So who wins North Carolina Central vs. Penn State, and which side hits in well over 60% of simulations? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has simulated this matchup 10,000 times!

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