No. 9 Vanderbilt vs. No. 20 Texas odds, line: 2025 college football picks for Week 10 predictions from proven model

The ninth-ranked Vanderbilt Commodores battle the No. 20 Texas Longhorns in a key Southeastern Conference matchup on Saturday. Vanderbilt is coming off a 17-10 win over Missouri last week, while Texas downed Mississippi State 45-38 in overtime. The Commodores (7-1, 3-1 SEC), who have won two in a row, are 3-1 against ranked opponents this season. The Longhorns (6-2, 3-1 SEC), who are on a three-game winning streak, are 1-1 against Top-25 teams. Texas quarterback Arch Manning (concussion) was removed from the injury report on Friday.

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Kickoff from DKR-Texas Memorial Stadium in Austin, Texas, is at noon ET. Vanderbilt leads the all-time series 8-4-1, but Texas won last year's meeting 27-24. The Longhorns are 3-point favorites in the latest Vanderbilt vs. Texas odds, while the over/under for total points scored is 44.5 via SportsLine consensus. 

Before making any Vanderbilt vs. Texas picks, be sure to check out the college football predictions and betting advice from the SportsLine Projection Model.

The model simulates every FBS game 10,000 times. Since its inception, it has generated a betting profit of over $2,000 for $100 players on its top-rated college spread football picks, and it enters Week 10 on a profitable 47-33 combined run on money-line and over/under picks since the beginning of 2024. Anyone following could have seen impressive returns.

The model has simulated Vanderbilt vs. Texas 10,000 times and the results are in. We can tell you that the model is leaning Over, and it also says one side of the spread hits in almost 60% of simulations.

So who wins Vanderbilt vs. Texas, and which side of the spread hits almost 60% of the time? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its college football picks!

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