No. 9 Oregon vs. No. 20 Iowa odds, line: 2025 college football picks for Week 11 predictions from proven model

The ninth-ranked Oregon Ducks will battle the 20th-ranked Iowa Hawkeyes in a key Big Ten Conference showdown on Saturday. Both teams are coming off their byes, after Oregon topped Wisconsin 21-7 and Iowa rolled over Minnesota 41-3. The Ducks (7-1, 4-1 Big Ten), who are 1-1 against ranked teams, are 3-0 on the road this year. The Hawkeyes (6-2, 4-1 Big Ten), who are 0-2 against ranked foes, are 4-1 on their home field.

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Kickoff from Kinnick Stadium in Iowa City, Iowa, is at 3:30 p.m. ET on CBS and Paramount+, where you can get a free 7-day trial. 

Oregon leads the all-time series 2-1. Oregon won the last meeting 40-18 in 1994. The Ducks are 5.5-point favorites in the latest Oregon vs. Iowa odds, while the over/under for total points scored is 42.5 via SportsLine consensus. 

Before making any Oregon vs. Iowa picks, be sure to check out the college football predictions and betting advice from the SportsLine Projection Model.

The model simulates every FBS game 10,000 times. Since its inception, it has generated a betting profit of over $2,000 for $100 players on its top-rated college spread football picks. Anyone following could have seen impressive returns.

The model has simulated Oregon vs. Iowa 10,000 times and the results are in. We can tell you that the model is leaning Over, and it also says one side of the spread hits in well over 50% of simulations.

So who wins Oregon vs. Iowa, and which side of the spread hits well over 50% of the time? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its college football picks!

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