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No. 9 Kentucky vs. No. 12 Louisville odds, prediction: 2025 Battle of the Bluegrass picks from proven model
SportsLine's model has locked in its best bets for Kentucky vs. Louisville in an NCAA men's basketball matchup on Tuesday night
A pair of heavyweights clash when the ninth-ranked Kentucky Wildcats take on the No. 12 Louisville Cardinals in the 58th edition of the Battle of the Bluegrass on Tuesday night. Kentucky is coming off a 107-59 win over Valparaiso on Friday, while Louisville downed Jackson State 106-70 on Thursday. The Wildcats (2-0), who tied for sixth in the SEC a year ago at 10-8 and were 24-12 overall, are 4-6 on the road since the start of last season. The Cardinals (2-0), who tied for second in the ACC at 18-2 and were 27-8 overall in 2024-25, are 16-3 on their home court since last November.
Tip-off from KFC Yum! Center in Louisville, Ky., is set for 8 p.m. ET. Kentucky leads the all-time series 40-17, including a 14-10 edge in games played at Louisville. Louisville is a 6.5-point favorite in the latest Kentucky vs. Louisville odds from SportsLine consensus, while the over/under for total points scored is 173.5.
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Before making any Kentucky vs. Louisville picks, check out the college basketball predictions from the SportsLine Projection Model.
The SportsLine Projection Model simulates every college basketball game 10,000 times and has returned over $2,200 in betting profit for $100 players on its top-rated college basketball picks over the past three seasons. Anyone following could have seen HUGE returns!
The model has simulated Kentucky vs. Louisville 10,000 times and the results are in. We can tell you that the model is leaning Under, and it also says one side of the spread hits over 50% of the time!
So who wins Kentucky vs. Louisville, and which side of the spread hits over 50% of the time? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that is up over $2,200 on top-rated CBB picks!
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