No. 7 Duke vs. Virginia odds, line: Proven college basketball model reveals spread pick for Wednesday's ACC showdown

The Duke Blue Devils can move one step closer to the ACC regular season title when they take on the rival Virginia Cavaliers in a key conference game on Wednesday at John Paul Jones Arena, in Charlottesville, Va. Ranked No. 7 in the country, the Blue Devils (23-4, 13-3 in ACC) lead the conference by one game over Notre Dame and own the tiebreaker over the Fighting Irish. Meanwhile the Cavaliers (17-10, 11-6) are tied for fifth in the ACC, 2.5 games behind Duke. 

Tip-off is set for 7 p.m. ET. The Blue Devils are favored by five points in the latest Duke vs. Virginia odds from Caesars Sportsbook, while the Over/Under for total points scored is 130. (See up-to-date odds for every game this week on our college basketball odds page.)

Before making any Virginia vs. Duke picks, be sure to check out what the SportsLine Projection Model has to say.

The SportsLine Projection Model simulates every Div. I college basketball game 10,000 times. Over the past five-plus years, the proprietary computer model has generated an impressive profit of almost $2,000 for $100 players on its top-rated college basketball picks against the spread. Anyone who has followed it has seen HUGE returns.

The model knows that Duke is one of the best teams in the country at moving and sharing the ball. The Blue Devils lead the ACC and rank ninth in the country in assists per game (17.4). They also lead the conference and rank third in the nation in assist-to-turnover ratio (1.62).

The model also knows that Virginia excels at keeping opponents off the scoreboard. The Cavaliers lead the ACC and rank 11th in the country in scoring defense (60.1 points allowed per game). Over their last six games, they have gone 5-1 and have allowed just 61.2 points per game.

Now, the model has set its sights on Duke vs. Virginia. We can tell you it is leaning Over the total, predicting a combined 136 points, and it also says one side of the spread covers in well over 50 percent of simulations! You ABSOLUTELY need to see it before locking in any college basketball picks.

Who wins Virginia vs. Duke? And which side of the spread covers in well over 50 percent of simulations? ... Join SportsLine right now to find out which side of the Duke vs. Virginia spread you should be all over Wednesday, all from the model on a roll on college basketball picks!