The No. 6 Ohio State Buckeyes (3-0) travel to face the No. 9 Notre Dame Fighting Irish (4-0) on Saturday at 7:30 p.m. ET. For this game, SportsLine consensus odds lists the Buckeyes as 3-point favorites, while the over/under is set at 55 (see up-to-date odds for every game this week on our college football odds page) in the latest Ohio State vs. Notre Dame odds. 

Before making any Ohio State vs. Notre Dame picks, you NEED to check out the college football predictions from the SportsLine Projection Model.

The SportsLine Projection Model simulates every FBS college football game 10,000 times. Since its inception, it has generated a stunning profit of nearly $2,500 for $100 players on its top-rated college football picks against the spread. Anyone who has followed it has seen HUGE returns.

The model has factored Ohio State's offense has a bunch of explosive and dynamic weapons. Junior receiver Marvin Harrison Jr. is leading the way for the Buckeyes. Harrison Jr. is a twitchy, fast and strong playmaker. The Pennsylvania native can blow past defenders and make plays vertically. Harrison Jr. has recorded 14 receptions for 304 yards and three touchdowns this season. He snagged five passes for 126 yards and one score in his last outing against Western Kentucky.

The model also knows Notre Dame senior quarterback Sam Hartman is off to a great start. The Wake Forest transfer has completed 71% of his pass attempts this season for 1,061 yards and 13 passing touchdowns. In last week's contest versus Central Michigan, Hartman tossed 330 yards and three touchdowns.

Now, it has set its sights on Ohio State vs. Notre Dame. We can tell you the model is leaning Over the total, and it also says one side of the spread hits in almost 60% of simulations! You ABSOLUTELY need to see it before locking in any college football picks.

Who wins Ohio State vs. Notre Dame, which side of the spread hits in almost 60% of simulations? ... Join SportsLine right now to find out which side of the Ohio State vs. Notre Dame spread you should be all over Saturday, all from the model that's up almost $2,500 on top-rated CFB spread picks since its inception!