No. 3 Michigan vs. No. 10 Illinois odds, prediction: 2026 Big Ten Conference men's college basketball picks from proven model

The third-ranked Michigan Wolverines will look to clinch the outright Big Ten Conference championship on Friday when they take on the 10th-ranked Illinois Fighting Illini. Michigan is coming off a 77-67 win over the Minnesota Golden Gophers on Tuesday, while Illinois dropped a 95-94 decision at UCLA on Saturday. The Wolverines (26-2, 16-1 Big Ten), who are 6-1 against ranked opponents, are 9-0 on the road this season. The Fighting Illini (22-6, 13-4 Big Ten), who are tied for second in the conference, are 13-2 on their home floor.

Tipoff from the State Farm Center in Champaign, Ill., is set for 8 p.m. ET. Illinois leads the all-time series 96-85, including wins in each of the last nine meetings. Michigan is a 1.5-point favorite in the latest Michigan vs. Illinois odds from DraftKings Sportsbook, while the over/under for total points scored is 157.5. 

Before making any Michigan vs. Illinois picks, check out the college basketball predictions from the SportsLine Projection Model.

The SportsLine Projection Model simulates every college basketball game 10,000 times and entered Week 17 on a sizzling 11-1 run on top-ranked over/under picks dating back to last year, and is on an 20-11 run on top-rated CBB side picks. Anyone following could have seen HUGE returns!

The model has simulated Michigan vs. Illinois 10,000 times and the results are in. The model is leaning Under, and it also says one side of the spread hits well over 70% of the time!

So who wins Michigan vs. Illinois, and which side of the spread hits well over 70% of the time? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has simulated this matchup 10,000 times!