The top two teams in the country meet for the Big Ten Conference Championship when the second-ranked Indiana Hoosiers battle the top-ranked Ohio State Buckeyes on Saturday. Indiana is coming off a 56-3 win at Purdue on Nov. 28, while Ohio State defeated Michigan 27-9 on Nov. 29. The Hoosiers (12-0, 9-0 Big Ten), who are appearing in their first Big Ten title game, are 2-0 against ranked opponents this season. The Buckeyes (12-0, 9-0 Big Ten), the defending national champions, are playing in their seventh conference championship game.

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Kickoff from Lucas Oil Stadium in Indianapolis is at 8 p.m. ET. Ohio State leads the all-time series 82-12-5, including a 38-14 win in 2024. The Buckeyes are 4.5-point favorites in the latest Indiana vs. Ohio State odds, while the over/under for total points scored is 48.5 via SportsLine consensus. 

Before making any Indiana vs. Ohio State picks, be sure to check out the college football predictions and betting advice from the SportsLine Projection Model.

The model simulates every FBS game 10,000 times, and it is profitable on its top-rated money-line and over/under picks since the beginning of the 2024 season. Anyone following could have seen impressive returns.

The model has simulated Indiana vs. Ohio State 10,000 times and the results are in. We can tell you that the model is leaning Under, and it also says one side of the spread has all the value!

So who wins Indiana vs. Ohio State, and which side of the spread has all the value? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its college football picks!

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