The No. 16 Texas A&M Aggies face the eighth-ranked Notre Dame Fighting Irish in a key non-conference matchup on Saturday night. Texas A&M defeated Utah State 44-22 last Saturday, while Notre Dame was beaten by Miami 27-24 on Aug. 31. The Aggies (2-0), who tied for fourth in the SEC at 5-3 and were 8-5 overall, were 2-2 on the road in 2024. The Fighting Irish (0-1), who were 14-2 overall and played for the national championship, were 6-1 on their home field.

Kickoff from Notre Dame Stadium in Notre Dame, Ind., is at 7:30 p.m. ET. Notre Dame leads the all-time series 4-2, including a 23-13 win last season. The Fighting Irish are 6.5-point favorites in the latest Texas A&M vs. Notre Dame odds, while the over/under for total points scored is 50.5 via SportsLine consensus. 

Before making any Texas A&M vs. Notre Dame picks, be sure to check out the college football predictions and betting advice from the SportsLine Projection Model.

The model simulates every FBS game 10,000 times. Since its inception, it has generated a betting profit of well over $2,000 for $100 players on its top-rated college spread football picks, and  was a profitable 31-19 combined on money-line and over/under college football picks in 2024. Anyone following at sportsbooks and on betting apps could have seen STRONG returns!

The model has simulated Texas A&M vs. Notre Dame 10,000 times and the results are in. We can tell you that the model is leaning Over, and it also says one side of the spread hits in well over 50% of simulations!

So who wins Texas A&M vs. Notre Dame, and which side of the spread hits well over 50% of the time? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its college football picks!