The 13th-ranked LSU Tigers look to end their four-game losing streak in the all-time series when they visit the Alabama Crimson Tide for an SEC matchup on Wednesday. LSU (15-2, 3-2) lost all three meetings between the rivals last season and hasn't defeated Alabama (11-6, 2-3) since posting a 90-76 victory at home on Jan. 29, 2020. 

Tipoff at the Coleman Coliseum in Tuscaloosa is set for 7 p.m. ET. The Crimson Tide are favored by 3.5 points in the latest Alabama vs. LSU odds from Caesars Sportsbook, while the over-under for total points scored is 148. (See up-to-date odds for every game this week on our college basketball odds page.)

Before making any LSU vs. Alabama picks, you NEED to check out the college basketball predictions from the SportsLine Projection Model.

The SportsLine Projection Model simulates every Division I college basketball game 10,000 times. Over the past five-plus years, the proprietary computer model has generated an impressive profit of over $2,400 for $100 players on its top-rated college basketball picks against the spread. Anyone who has followed it has seen HUGE returns.

The model knows LSU struggled down the stretch against Arkansas on Saturday and suffered a 65-58 loss, ending its 13-game winning streak at home. The Tigers were outscored 17-2 over the final nine minutes as they missed eight of their nine field-goal attempts and committed six turnovers. Senior forward Darius Days, who is second on the team in scoring (14 points per game), was limited to a season-low three points on 1-of-8 shooting as LSU received more production from its bench (30 points) than its starters (28).

The model also knows Alabama enters with a three-game losing streak after dropping a 78-76 decision at Mississippi State on Saturday. The Crimson Tide shot just 39.3 percent from the floor and finished 8-for-29 from beyond the arc as senior guard Keon Ellis missed a 3-point attempt at the buzzer. Five of Alabama's six losses this season, including all three during its current skid, have been by six points or fewer.

Now, the model has set its sights on LSU vs. Alabama. We can tell you it is leaning Over the total, and it also says one side of the spread covers in well over 60 percent of simulations! You ABSOLUTELY need to see it before locking in any college basketball picks.

Who wins LSU vs. Alabama? And which side of the spread covers in well over 60 percent of simulations? ... Join SportsLine right now to find out which side of the Alabama vs. LSU spread you should be all over Wednesday, all from the model on a roll on college basketball picks!