No. 11 Gonzaga vs. No. 18 Kentucky odds, prediction: 2025 men's college basketball picks from proven model

Two ranked teams looking to get back on track meet when the 11th-ranked Gonzaga Bulldogs face the 18th-ranked Kentucky Wildcats in a key early-season non-conference matchup. Gonzaga suffered a 101-61 setback against Michigan on Wednesday, while Kentucky dropped a 67-64 decision against North Carolina on Tuesday. The Zags (7-1), who finished second in the West Coast Conference at 14-4 and were 26-9 overall a year ago, are 2-1 against ranked foes. The Wildcats (5-3), who tied for sixth in the Southeastern Conference at 10-8 and were 24-12 overall, are 0-3 against ranked opponents.

Tipoff from Bridgestone Arena in Nashville is set for 7 p.m. ET as part of the 2025 Music City Madness event. The all-time series is tied 2-2, but Kentucky rallied from 16 points down at the half to defeat Gonzaga 90-89 in overtime at Seattle last season. Gonzaga is a 5.5-point favorite in the latest Gonzaga vs. Kentucky odds from SportsLine consensus, while the over/under for total points scored is 160.5.

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Before making any Gonzaga vs. Kentucky picks, check out the college basketball predictions from the SportsLine Projection Model.

The SportsLine Projection Model simulates every college basketball game 10,000 times and has returned over $2,000 in betting profit for $100 players on its top-rated college basketball picks over the past three-plus seasons. Anyone following could have seen HUGE returns!

The model has simulated Gonzaga vs. Kentucky 10,000 times and the results are in. We can tell you that the model is leaning Over, and it also says one side of the spread hits in more than 70% of simulations!

So who wins Gonzaga vs. Kentucky, and which side hits more than 70% of the time? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has simulated this matchup 10,000 times!

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