NFL Week 9 odds, score predictions: SportsLine AI reveals picks for every game

A pair of AFC division leaders headline the NFL Week 9 schedule when the Indianapolis Colts take on the Pittsburgh Steelers on Sunday. The Colts, behind running back Jonathan Taylor and quarterback Daniel Jones, have taken command of the AFC South at 7-1. Pittsburgh, meanwhile, is in control of the AFC North at 4-3, but have dropped two in a row. Quarterback Aaron Rodgers is coming off a disappointing performance in a loss to the Green Bay Packers, a team he spent 18 years with. Indianapolis enters as a 3-point favorite and is one of seven road favorites during the Week 9 NFL schedule.

Another matchup involving contenders sees the Kansas City Chiefs (4-3) visiting the Buffalo Bills (5-2). The Chiefs are 1.5-point favorites as former MVP quarterbacks Patrick Mahomes and Josh Allen square off for the 10th time. Mahomes holds a 5-4 edge, but Allen and the Bills have won each of the last four regular season meetings. The largest spread is New Orleans at Los Angeles Rams (-14), as New Orleans QB Tyler Shough will make his first career start, followed by Panthers vs. Packers (-13.5) and Los Angeles Chargers at Tennessee (+9.5). The slimmest spread sees the Texans (-1.5) as home favorites over the Broncos.

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Before making any Week 9 NFL picks, be sure to check out the NFL score predictions from the SportsLine's self-learning AI.

Built using cutting-edge artificial intelligence and machine learning techniques by SportsLine's Data Science team, AI Predictions and AI Ratings are generated for each game. The AI predictions are determined by statistically learning from each team's historical data then quantitatively evaluating the strength of the opponents defense by assigning a numeric value out of 100 called a matchup score. 

Once a prediction is formulated, the AI rating is generated using the prediction, the matchup score, and the odds of the market. For example, you could see a 5-star rating on an Over bet if a team is facing a poor defense, their prediction differs from the line and there are favorable odds.

In addition, SportsLine AI is the first fully automated predictive model at SportsLine. It continuously refreshes on the most recent available data and can help you spot the biggest discrepancies in the lines. SportsLine's AI has nailed more than 2,000 4.5- and 5-star prop picks since the start of the 2023 season! Anyone who has followed it is WAY UP!

After analyzing every game in Week 9, the AI says the Steelers (+3, 50.5), who have Aaron Rodgers at quarterback, cover comfortably against the Colts. Rodgers has been solid. In seven starts, he has completed 68.3% of his passes for 1,489 yards and 16 touchdowns with five interceptions. SportsLine AI rates the Steelers as an A pick on the money line and also predicts a 28-26 win on average.

SportsLine AI has generated against the spread, over/under and money-line picks for every game in Week 9! In fact, the AI has generated well over 20 HIGHLY-COVETED A+ picks! You ABSOLUTELY NEED to see the AI analysis before making any Week 9 NFL bets.

Which NFL bets do you need to make NOW for Week 9? And which must-see NFL picks are worthy of an A+ rating? ... Join SportsLine now to see the top 2025 Week 9 NFL picks, all from the self-learning SportsLine AI that has nailed a COLOSSAL 2,000+ top-rated picks since the start of last season!

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