The Week 3 NFL schedule has a number of key matchups, including six divisional matchups, including an AFC West clash between the Denver Broncos and Los Angeles Chargers (-3). Others include Falcons vs. Panthers (+5.5), Colts vs. Titans (+4.5), Cardinals vs. 49ers (-2.5) and Texans vs. Jaguars (-1.5), which has the slimmest Week 3 NFL line as bettors search for the best opportunities to maximize returns. Point spread, point total, and money-line bets remain staples, and uncovering true value in the Week 3 odds requires a deeper look. 

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Before you make any Week 3 NFL picks, be sure to check out the NFL score predictions from the SportsLine computer simulation model.

The model, which simulates every NFL game 10,000 times, is up well over $7,000 for $100 players on top-rated NFL picks since its inception. The model is on a 37-17 run on top-rated picks dating back to 2024. Anybody following could have seen HUGE returns!

After analyzing every game in Week 3, the model says the Packers beat the Bills 28-14, comfortably covering the 7.5-point spread in a game that goes Over 41.5 total points. 

SportsLine's model has generated against the spread, over/under, and money-line picks for every game in Week 3! In fact, the model has generated five HIGHLY-COVETED A-graded picks! You ABSOLUTELY NEED to see the Model's analysis before making any Week 3 NFL bets.

Which NFL bets do you need to make NOW for Week 3, and which must-see NFL picks are worthy of an A rating? ... Join SportsLine now to see the top 2025 Week 3 NFL picks, all from the SportsLine model that is up well over $7,000 for $100 players on top-rated NFL picks since its inception!

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