Playoff spots will be on the line in Week 17, with four teams capable of clinching a spot in the NFL playoff picture. In the AFC, the Dolphins (8-7) can secure a spot in the postseason with a win or a Jets loss or tie. In the NFC, the Giants (8-6-1), Buccaneers (7-8) and Commanders (7-7-1) can all make their way into the playoffs. However the game of the week arguably takes place on Monday night when the Bengals (11-4) host the Bills (12-3). Before you make any Week 17 NFL picks or NFL parlays, you need to see what SportsLine senior analyst Larry Hartstein has to say.

A former lead writer for Covers and The Linemakers, Hartstein combines a vast network of Vegas sources with an analytical approach he honed while working for Pro Football Focus. He entered the 2022 NFL season 427-344 all-time on NFL side picks (plus $3,764 for $100 players), including 394-330 against the spread. Hartstein went 68-50 ATS and 8-3 on money-line plays last season for a profit of $1,552.

Hartstein also is 28-19-1 on his best bets this season, including 22-13-1 the past 12 weeks. Now, Hartstein has locked in three confident Week 17 NFL best bets. If you successfully parlay his picks, you're looking at a payout of almost 6-1.

We can tell you Hartstein loves the Lions to cover against the Bears. "The Bears also are decimated on the offensive line and at receiver," Hartstein told SportsLine.

Hartstein also has locked in two other spread picks, including a play on a team with a run game that "should keep clicking" this week. You ABSOLUTELY need to see his picks before betting on NFL Week 17!

So what are Hartstein's Week 17 NFL best bets? And which team with a strong run game is a must-play? ... Join SportsLine right now to see Larry Hartstein's Week 17 NFL best bets, all from the expert on a 22-13 roll!