The Week 1 NFL schedule is loaded with marquee matchups such as Lions vs. Packers (-1.5), Bills vs. Ravens (-1) on Sunday night and Bears vs. Vikings (-1.5) on Monday night, as bettors are searching for the best opportunities to maximize returns. Point spread, point total, and money-line bets remain staples, and uncovering true value in the Week 1 odds requires a deeper look. 

LIMITED TIME: Use promo code CHAMPIONSHIP to get your first month for $1 JOIN NOW. 

Before you make any Week 1 NFL picks, be sure to check out the NFL score predictions from the SportsLine computer simulation model.

The model, which simulates every NFL game 10,000 times, is up well over $7,000 for $100 players on top-rated NFL picks since its inception. The model went 31-15 on top-rated picks in 2024. Anyone following has seen HUGE returns!

After analyzing every game in Week 1, the model says the Commanders cover comfortably as 6.5-point home favorites against the Giants on Sunday. The Model rates a Commanders cover as an A-graded pick, predicting a final score of 32-21 in Washington's favor.

SportsLine's model has generated against the spread, over/under, and money-line picks for every game in Week 1! In fact, the model has generated four HIGHLY-COVETED A-graded picks! You ABSOLUTELY NEED to see the Model's analysis before making any Week 1 NFL bets.

Which NFL bets do you need to make NOW for Week 1? And which must-see NFL picks are worthy of an A rating? ... Join SportsLine now to see the top 2025 Week 1 NFL picks, all from the SportsLine model that is up well over $7,000 for $100 players on top-rated NFL picks since its inception!

LIMITED TIME: Use promo code CHAMPIONSHIP to get your first month for $1 JOIN NOW.