NFL odds, lines, spreads: 2025 Week 9 picks, predictions from proven model

The Rams are 5-0 both straight up and against the spread versus non-conference opponents this year, but they're 0-2 SU and ATS versus NFC teams. Thus, the Week 9 NFL schedule having L.A. facing another NFC squad in the Saints will intrigue many when contemplating Week 9 NFL bets. The Rams are 14-point favorites, per the latest NFL odds, while other conference matchups include Jaguars vs. Raiders (+2.5), Steelers vs. Colts (-3.5), Packers vs. Panthers (+13.5) and Seahawks vs. Commanders (+3).

There's just one divisional contest in Lions vs. Vikings, a rivalry which has seen Detroit win five straight. The home Lions are at -8.5 to make Week 9 NFL picks on, and it may be helpful to your NFL betting strategy to know that Detroit has also covered in each of the last five meetings. Additionally, though Chiefs vs. Bills isn't a divisional matchup, it's a rivalry game, no less, with Kansas City favored by 2 points in a road tilt on Sunday at 4:25 p.m. ET.

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The week's schedule concludes with Cowboys vs. Cardinals on Monday night. Jacoby Brissett is slated to get his third start in place of Kyler Murray (foot). With Arizona's five-game losing streak being the longest in the league, the Cowboys are 3-point favorites per the Week 9 NFL spreads, despite Arizona winning seven of the last eight meetings.

Before locking in any NFL bets, make sure you see what SportsLine's advanced computer model has to say. 

The model, which simulates every NFL game 10,000 times, is up well over $7,000 for $100 players on top-rated NFL picks since its inception. The model enters Week 9 on a sizzling 45-28 run on top-rated picks dating back to 2024. Anybody following could have seen HUGE returns!

Now, the model has evaluated the latest NFL odds, simulated every snap for Week 9 of the 2025 NFL season, and the results are in.

We can tell you one of the model's strongest Week 9 NFL picks is that the Texans (+1.5, 40.5) cover at home versus the Broncos in a Sunday 1 p.m. ET kickoff. The model has Houston prevailing versus the spread well over 50% of the time. Another one of its Week 9 NFL predictions: the Chargers (-9.5, 43.5) cover versus the Titans in nearly 60% of simulations. The model also says the Over hits in over 50% of simulations.

The model has also made the call on who wins and covers in every other NFL game this week and just revealed FOUR teams that outright win by double digits! You ABSOLUTELY NEED to see its NFL picks for every game before you make any NFL bets of your own!

So which NFL teams should you back in Week 9, and which four teams should you lock in RIGHT NOW? ... Join SportsLine now to see who wins and covers every single NFL game this week, all from the model on 45-28 roll on top-rated NFL picks!

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