The Indianapolis Colts look to keep control of the AFC South race when they travel to Los Angeles to battle the Chargers in a key AFC matchup between conference contenders. Both teams are 4-0 against AFC foes in 2025. The Colts are coming off a 31-27 win over the Arizona Cardinals for their second win in a row. The Chargers (4-2), who lead the AFC West, pulled out a 29-27 win over the Miami Dolphins. The Chargers enter as 2.5-point favorites in one of four games with a Week 7 NFL spread of 2 points or fewer while another is Jets vs. Panthers (-1.5).

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Quarterback Daniel Jones is coming off a solid performance in the win over the Cardinals. He not only completed 22 of 30 passes for 212 yards and two touchdowns with one interception, he also rushed five times for 20 yards and a score. There are a number of intriguing matchups on the Week 7 NFL schedule, including Eagles vs. Vikings (+2.5), Packers vs. Cardinals (+7), Commanders vs. Cowboys (-1.5), and Buccaneers vs. Lions (-5.5) on Monday Night Football. 

Which other teams have value to include in Week 7 NFL parlay bets, and which side of the NFL odds should you target?

Before you lock in any NFL bets, make sure you see what SportsLine's advanced computer model has to say. 

The model, which simulates every NFL game 10,000 times, is up well over $7,000 for $100 players on top-rated NFL picks since its inception. The model is on a sizzling 42-25 run on top-rated picks dating back to 2024. Anybody following could have seen HUGE returns!

The model has scoured the Week 7 NFL odds and locked in five confident NFL best bets. If you successfully parlay its sports betting picks, you'd be looking at a massive payout of around 24-1. 

One pick we'll give away: The model is backing the Bears (-4.5) to cover against the Saints 64% of the time.

The model is also backing a surprising underdog that it says will not only cover, but win outright! You ABSOLUTELY NEED to see its NFL picks for every game before you make any NFL bets of your own!

So which NFL teams should you back in Week 7, and which five picks should you lock in RIGHT NOW? ... Join SportsLine now to see who wins and covers every single NFL game this week, all from the model on a 42-25 roll on top-rated NFL picks!

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