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NFL odds, lines, spreads: 2025 Week 15 picks, predictions from proven model: 5-way parlay pays 25-1

The SportsLine Projection Model, which is up well over $7,000 for $100 players on top-rated NFL picks since its inception, has revealed its Week 15 NFL 25-1 parlay

ByUpdated: Dec 08, 2025 4:59PM UTC . 2 min read

The NFL Week 15 schedule is full of playoff implications. Among them is the AFC West matchup between Justin Herbert and the Los Angeles Chargers vs. Patrick Mahomes and the Kansas City Chiefs. Los Angeles is in the thick of the AFC West race, while the Chiefs need a strong finish and a lot of help to reach the postseason for an 11th consecutive year. Kansas City is a 4.5-point favorite and is 4-6 against the spread in its last 10 games, while Los Angeles is 3-6-1 ATS in their last 10. The Chargers won the last meeting, 27-21, in Brazil on Sept. 5.

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There are a number of other solid matchups on the Week 15 NFL schedule, including Bills (-1.5) vs. Patriots, Ravens (-2.5) vs. Bengals, Packers (-2) vs. Broncos, Lions vs. Rams (-5.5) and Colts vs. Seahawks (-11.5) on Sunday, and Vikings vs. Cowboys (-6) on Sunday Night Football.

Before locking in any NFL bets, make sure you see what SportsLine's advanced computer model has to say. 

The model, which simulates every NFL game 10,000 times, is up well over $7,000 for $100 players on top-rated NFL picks since its inception. The model entered Week 14 on a 49-33 run on top-rated picks dating back to 2024. Anybody following could have seen HUGE returns!

The model has scoured the Week 14 NFL odds and locked in five confident NFL best bets. If you successfully parlay its sports betting picks, you'd be looking at a massive payout of around 25-1. 

One pick we'll give away: The model is backing the Cowboys (-6, 47.5) to cover against the Vikings nearly 60% of the time.

The model is also backing a surprising underdog that it says will cover in a tight matchup! You ABSOLUTELY NEED to see its NFL picks for every game before you make any NFL bets of your own!

So which NFL teams should you back in Week 15, and which five picks should you lock in RIGHT NOW? ... Join SportsLine now to see who wins and covers every single NFL game this week, all from the model on a 49-33 roll on top-rated NFL picks!

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Daniel Kohn

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