NFL odds, lines, spreads: 2025 Week 11 picks, predictions from proven model: 5-way parlay pays almost 25-1

An eye-popping nine divisional games highlight the NFL Week 11 schedule. Among the most intriguing pits the Seattle Seahawks (7-2) against the Los Angeles Rams (7-2) with first place in the NFC West on the line. Another huge matchup has the nine-time defending AFC West-champion Kansas City Chiefs (5-4) battling the Denver Broncos (8-2), who hold the top spot in the division. The Rams enter as 3-point favorites as both Los Angeles and Seattle are 7-2 against the spread this season, tying them for the best NFL spread marks. The Chiefs, meanwhile, are 4.5-point favorites after the line opened at Kansas City -3.5.

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There are a number of other intriguing matchups on the Week 11 NFL schedule, including Bears vs. Vikings (-3), Buccaneers vs. Bills (-5.5), Bengals vs. Steelers (-5.5) and 49ers vs. Cardinals (+3), with Brock Purdy returning to the lineup for the Niners.

Before locking in any NFL bets, make sure you see what SportsLine's advanced computer model has to say. 

The model, which simulates every NFL game 10,000 times, is up well over $7,000 for $100 players on top-rated NFL picks since its inception. The model is on a sizzling 47-29 run on top-rated picks dating back to 2024. Anybody following could have seen HUGE returns!

The model has scoured the Week 11 NFL odds and locked in five confident NFL best bets. If you successfully parlay its sports betting picks, you'd be looking at a massive payout of around 24-1. 

One pick we'll give away: The model is backing the Cowboys (-3.5, 50) to cover against the Raiders 60% of the time.

The model is also backing a surprising underdog that it says will cover in a tight matchup! You ABSOLUTELY NEED to see its NFL picks for every game before you make any NFL bets of your own!

So which NFL teams should you back in Week 11, and which five picks should you lock in RIGHT NOW? ... Join SportsLine now to see who wins and covers every single NFL game this week, all from the model on a 47-29 roll on top-rated NFL picks!

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