The Week 6 NFL schedule is here, and NFL bettors are looking for ways to get the biggest returns. While spread, total and money-line picks remain popular, there's a growing popularity for props, alternate lines with both the spread and total, exact score predictions and other plus-money returns. 

With so many highly-anticipated matchups on the Week 6 NFL schedule like Rams vs. Ravens (+7.5), with Baltimore without Lamar Jackson and 49ers vs. Buccaneers (-3) in a matchup of teams with 3-2 ATS records. There's also a potential Super Bowl preview in Lions vs. Chiefs (-2.5) on 'Sunday Night Football,' two games -- Bills vs. Falcons (+4.5) and Bears vs. Commanders (-4.5) -- on 'Monday Night Football,' and parity around the league at an all-time high, finding value in the Week 6 odds can take some extra digging.

Effectively building parlays can pay off big in your NFL betting strategy. Before making your Week 6 NFL picks and parlays, you NEED to see the Week 5 NFL parlay from SportsLine's proven computer simulation model and top-rated experts that could return more than $44,600 for a $10 bettor. 

The model, which simulates every NFL game 10,000 times, is up well over $7,000 for $100 players on top-rated NFL picks since its inception. The model is on a sizzling 41-21 run on top-rated picks dating back to 2024. Anybody following could have seen HUGE returns!

For Week 6, one of the picks featured in the 5-leg parlay is the Indianapolis Colts, who are listed as -7 favorites on the standard spread, covering the alternate spread of -9.5 against the Arizona Cardinals, returning +160. 

The parlay also includes four other picks from the SportsLine computer simulation model, including a first touchdown scorer prop that returns +1100! You ABSOLUTELY need to see these picks before locking in any NFL picks of your own.

What are the top NFL picks for Week 6 that can be combined into a parlay that returns well over $44k for $10 bettors? ... Join SportsLine now to see the top NFL picks this week and best bets from SportsLine's proven computer simulation model, and find out!

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