The Tennessee Titans visit the AFC East-champion New England Patriots for a Wild-Card matchup on Saturday night. Kickoff from Gillette Stadium is set for 8:15 p.m. ET. New England is a 4.5-point favorite, while the Over-Under for total points scored is 45.

Before you make any Patriots vs. Titans picks and NFL predictions, see what SportsLine's NFL expert, Larry Hartstein, has to say. 

A former lead writer for Covers and The Linemakers, Hartstein combines a vast network of Vegas sources with an analytical approach he honed while working for Pro Football Focus. Last year, he went 61-47 in the NFL, and this season, he posted a 54-35 record against the spread for a 61 percent cash rate that returned his followers nearly $1,550.

In addition, he has a particularly keen eye for the Titans. In fact, Hartstein is a BLISTERING 10-3 in his last 13 picks for or against the Titans, hitting each of the last four - including Week 17! Anyone who has followed him is WAY up.

We can tell you Hartstein is leaning Over on Saturday night, but his much stronger play is on the spread. Hartstein has found a crucial x-factor that has him going BIG on one side. You ABSOLUTELY need to see it before locking in your own picks.

Who wins Patriots vs. Titans? And what crucial x-factor makes one side of the spread a MUST-BACK? ... Join SportsLine right now to see which side of the Patriots vs. Titans spread you need to back on Saturday, all from the acclaimed expert who's an impressive 10-3 on Titans picks!