The Denver Broncos and Indianapolis Colts will meet on Thursday Night Football. Veteran quarterbacks Matt Ryan and Russell Wilson will appear in Thursday's NFL DFS player pool. Top pass-catchers like Jerry Jeudy and Michael Pittman are also among potential NFL DFS picks. Before setting your NFL DFS lineups on sites like DraftKings or FanDuel, you NEED to see what Mike McClure has to say.

McClure is a legendary professional DFS player with over $2 million in career winnings. His methodology has led to enormous cashes on FanDuel and DraftKings. He took down two high-stakes tournaments on FanDuel in 2020 and recorded a pair of top-10 finishes in tournaments with over 130,000 entrants on DraftKings. His lineups also finished inside the top 1% in more than a dozen other tournaments.

He uses a powerful prediction model that simulates every snap of NFL action, taking factors such as matchups, statistical trends and injuries into account. This allows him to find the best DFS values that he shares only with members at SportsLine.

This year, he's already won the DraftKings Millionaire Maker, crushing the Rams vs. 49ers Monday Night Football game. Now, McClure has turned his attention to Colts vs. Broncos and locked in his top daily Fantasy football picks. 

We can tell you that Colts running back Nyheim Hines is one of McClure's top NFL DFS picks for Thursday Night Football in Week 5. Part of McClure's optimal NFL DFS strategy also includes rostering Broncos quarterback Russell Wilson, who has yet to hit his stride under new Broncos head coach Nathaniel Hackett, but had a productive game in last week's loss to Las Vegas. Against the Raiders, Wilson completed 68 percent of his passes and finished with two passing touchdowns and another score on the ground.

McClure is also targeting a player who could go off for MASSIVE numbers on Thursday Night Football! This pick could be the difference between winning your tournaments and cash games or going home with nothing! You ABSOLUTELY need to see who it is before locking in any lineups.

What are the top NFL DFS picks for Colts vs. Broncos on Thursday Night Football? And which player is a MUST-ROSTER? ... Join SportsLine now to see DFS pro Mike McClure's top picks, stacks, and player pools for FanDuel and DraftKings, and cash in BIG on NFL DFS!