The Week 7 NFL schedule opens with Kyler Murray, DeAndre Hopkins and the Arizona Cardinals hosting Alvin Kamara, Chris Olave and the New Orleans Saints on Thursday Night Football. In a game with plenty of offensive firepower on both sides, you'll need to find the right mix of players for your TNF NFL DFS picks. Before locking in any Cardinals vs. Saints Showdown NFL DFS lineups for Thursday Night Football on sites like DraftKings and FanDuel, you NEED to see what SportsLine's Jimmie Kaylor has to say.

Kaylor is a NFL and DFS expert for SportsLine, who opened the 2022 NFL season by winning DraftKings' NFL Showdown Thursday Kickoff Millionaire contest. He edged out over 355,000 other entrants in the contest and also has multiple five-figure tournament wins on his DFS resume. Kaylor has covered the NFL and college football for close to a decade as a member of the Pro Football Writers of America, and his background as a former college and NFL player gives him a unique perspective when building his fantasy lineups and locking in his betting picks.  

Kaylor has been spot-on all season, hitting on epic NFL DFS picks like Jerry Jeudy (4-102-1), Stefon Diggs (12-148-3), Amari Cooper (7-101-1), Nick Chubb (23-113-1), CeeDee Lamb (8-87-1), Deebo Samuel (6-115-1) Cooper Kupp (14-122), Travis Kelce (7-25-4) and Davante Adams (3-124-2) in primetime.

Now, Kaylor has turned his attention to Cardinals vs. Saints on Week 7 Thursday Night Football and locked in his top daily Fantasy football picks.

We can tell you that one of Kaylor's top NFL DFS picks for the Saints-Cardinals TNF matchup is Arizona All-Pro wide receiver DeAndre Hopkins. "(DeAndre) Hopkins is making his season debut after serving a six-game suspension, so there may be some rust to knock off early. That said, the 30-year-old wideout didn't have to grind through training camp, and should come into this matchup with fresh legs and be close to 100% healthy. He also is very familiar with quarterback Kyler Murray, and with Hollywood Brown out, the targets should be there for Hopkins to produce huge numbers on Thursday Night Football."

Kaylor is also targeting another under-the-radar option for TNF who could post HUGE numbers and carry your lineups to victory on Thursday night. This pick could be the difference between winning your tournaments and cash games or going home with nothing! You ABSOLUTELY need to see who it is before locking in any lineups.

What are the top NFL DFS picks for Saints vs. Cardinals on FanDuel and DraftKings? And which player is a MUST-ROSTER? ... Join SportsLine now to see NFL expert and DraftKings Millionaire winner Jimmie Kaylor's top picks, stacks, and player pools for FanDuel and DraftKings, and cash in BIG on NFL DFS!