Many of the NFL's biggest stars shone brightly in the opening week, including Christian McCaffrey and Tyreek Hill. Those who slotted them into NFL DFS lineups were surely rewarded, and they'll look for the same kind of success with their Week 2 daily Fantasy football lineups. Before making any Week 2 NFL DFS picks on sites like DraftKings and FanDuel, you NEED to hear what SportsLine daily Fantasy expert Mike McClure has to say.

McClure is a legendary professional DFS player with over $2 million in career winnings. His methodology has led to enormous cashes on FanDuel and DraftKings. He took down two high-stakes tournaments on FanDuel in 2020 and recorded a pair of top-10 finishes in tournaments with over 130,000 entrants on DraftKings. His lineups also finished inside the top 1% in more than a dozen other tournaments.

He uses a powerful prediction model that simulates every snap of NFL action, taking factors such as matchups, statistical trends and injuries into account. This allows him to find the best DFS values that he shares only with members at SportsLine.

Last year, he won the DraftKings Millionaire Maker twice and the FanDuel Million once. Now, McClure has turned his attention to the Week 2 NFL DFS slate and locked in his top daily Fantasy football picks.

We can tell you one of McClure's top NFL DFS picks for Week 2 is Titans running back Derrick Henry at $7,400 on DraftKings and $8,300 on FanDuel. Part of McClure's optimal NFL DFS strategy also includes rostering Bengals receiver Ja'Marr Chase at $7,900 on DraftKings and $8,400 on FanDuel. Chase has seven touchdowns over his last eight games, and his 84.7 receiving yards per game is fourth-best in NFL history (min. 30 games).

McClure is also targeting a player who could go off for MASSIVE numbers in Week 2! This pick could be the difference between winning your tournaments and cash games or going home with nothing! You ABSOLUTELY need to see who they are before locking in any lineups.

What are the top NFL DFS picks for Week 2? And which player is a MUST-ROSTER? ... Join SportsLine now to see DFS pro Mike McClure's top picks, stacks, and player pools for FanDuel and DraftKings, and cash in BIG on NFL DFS!