Week 4 of the NFL season will see several high-profile matchups featuring star quarterbacks in the NFL DFS player pool. In Sunday's early slate, Josh Allen and Lamar Jackson will share the field in Bills vs. Ravens, and then in the late window, Russell Wilson and Derek Carr will have their first divisional contest versus one another.

Before you set your Week 4 NFL DFS lineups, you NEED to hear what SportsLine daily Fantasy expert Mike McClure has to say.

McClure is a legendary professional DFS player with over $2 million in career winnings. His methodology has led to enormous cashes on FanDuel and DraftKings. He took down two high-stakes tournaments on FanDuel in 2020 and recorded a pair top-10 finishes in tournaments with over 130,000 entrants on DraftKings. His lineups also finished inside the top one percent in more than a dozen other tournaments last season.

He uses a powerful prediction model that simulates every snap of NFL action, taking factors such as matchups, statistical trends and injuries into account. This allows him to find the best DFS values that he shares only with members at SportsLine.

In Week 3, McClure had Eagles quarterback Jalen Hurts as one of his core NFL DFS picks for both FanDuel and DraftKings: The result: Hurts had 340 passing yards, 20 rushing yards and three passing touchdowns, returning 30.6 points on DraftKings and 27.6 points on FanDuel. Anybody who had him in their lineups was well on the way to a HUGE day.

We can tell you one of McClure's top NFL DFS picks for Week 4 is Seahawks receiver Tyler Lockett at $5,900 on DraftKings and $6,900 on FanDuel. Part of McClure's optimal NFL DFS strategy includes rostering Lions running Jamaal Williams at $6,100 on DraftKings and $7,400 on FanDuel. Williams is tied for the NFL lead with four touchdowns and has averaged 65.7 scrimmage yards per game. With D'Andre Swift (shoulder) expected to sit, Williams should be the bell cow back on Sunday versus Seattle.

McClure is also targeting a player who could go off for MASSIVE numbers in Week 4! This pick could be the difference between winning your tournaments and cash games or going home with nothing! You ABSOLUTELY need to see who they are before locking in any lineups.

What are the top NFL DFS picks for Week 4? And which player is a MUST-ROSTER? ... Join SportsLine now to see DFS pro Mike McClure's top picks, stacks, and player pools for FanDuel and DraftKings, and cash in BIG on NFL DFS!