NCAA Tournament Sweet 16 picks: College basketball expert reveals 2026 March Madness predictions

March Madness 2026 continues with the Sweet 16, starting on Thursday. We've seen mostly chalk thus far in the 2026 NCAA Tournament, as each region consists of three of the top four seeded teams, along with a lone outlier. The likes of No. 5 St. John's, No. 6 Tennessee, No. 9 Iowa and No. 11 Texas have already pulled off March Madness upsets, but will those trends continue in the Sweet 16 bracket?

There are still heavy hitters to back with college basketball picks, including 1-seeds Duke, Arizona and Michigan. Who will survive and advance during the second weekend of the NCAA Tournament 2026? Before making any college basketball picks or filling out a 2026 March Madness Sweet 16 bracket, you NEED to see what red-hot college basketball expert Thomas Casale has to say.