NC State vs. South Florida odds, line, spread: Proven model reveals college football picks, predictions for Week 1, 2021

The NC State Wolfpack will take on the South Florida Bulls at 7:30 p.m. ET on Thursday at Carter-Finley Stadium. The Wolfpack ended last year with an 8-4 record, while South Florida finished the season at 1-8. The Wolfpack are favored by 18.5-points in the latest NC State vs. South Florida odds from Caesars Sportsbook, and the over-under is set at 59. 

Before you make any South Florida vs. NC State picks, you'll want to see the college football predictions from the SportsLine Projection Model.

The SportsLine Projection Model simulates every FBS college football game 10,000 times. Over the past five-plus years, the proprietary computer model has generated a stunning profit of over $3,600 for $100 players on its top-rated college football picks against the spread. It also enters Week 1 of the 2021 season on a 57-37 run on all top-rated college football picks. Anyone who has followed it has seen huge returns.

Now, it has simulated NC State vs. South Florida 10,000 times and the results are in. We can tell you that the model is leaning Under, and it's also generated a point-spread pick that is hitting in over 60 percent of simulations. You absolutely need to see it before locking in your own picks.

So who wins NC State vs. South Florida? And which side of the spread is a must-back? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its college football picks.