NBA odds, lines, spreads, picks, predictions for Tuesday, April 21: NBA longshot parlay returns over +15000000

The first Tuesday of the 2026 NBA playoffs has a three-game slate, so there are plenty of options to choose NBA longshot picks for an NBA parlay. From first scorer props to margins of victory to predicting if a player will have a double-double or triple-double, there are a bevy of predictions one can include. Eight of the 11 postseason games thus far have been decided by double-digits, so predicting a winning margin of over 10 points could be an NBA bet that's a part of your playoff parlay.

Houston winning by 11+ points over the Lakers would return +160, while the Lakers winning by more than 10 points would net +500. Which combination of player props and NBA predictions should comprise your Tuesday NBA parlay?

Before locking in any NBA bets or parlays, make sure you see what SportsLine's advanced computer model has to say. 

SportsLine's model simulates every NBA game 10,000 times and has returned well over $10,000 in betting profit for $100 players on its top-rated NBA picks over the past eight-plus seasons. The model entered first full week of the 2026 NBA playoffs on a sizzling 24-9 roll (73%) on top-rated NBA spread picks dating back to last season. Anyone following could have seen HUGE returns!

The model has evaluated the Tuesday NBA odds and locked in six confident NBA best bets. If you successfully parlay them you'd be looking at a big payout of over +15000000.

One pick we'll give away: The model is backing San Antonio's De'Aaron Fox to score 20+ points at +190. The model projects Fox to have 20.2 points in Game 2 versus Portland.

The model has also locked in five more strong picks, including a first scorer prop that has a massive return over +3000 in a longshot parlay that pays over $1.5 million on just a $10 bet! You ABSOLUTELY need to see it right now.

So what are the NBA best bets for Tuesday's longshot parlay that could unlock a payday of over $1.5 million on just a $10 bet? ... Join SportsLine now to see who wins and covers every single NBA game this week, all from the model that's on a 24-9 run on top-rated NBA picks!