The New York Yankees continue their highly anticipated four-game home series with the Houston Astros on Friday night as part a full MLB schedule. The Yankees rallied to win the opener 7-6 with a four-run ninth inning capped by Aaron Judge's game-winning single. New York (52-18) has the best record in MLB and a 12.5-game lead in the AL East, while the Astros (43-26) are 9.5 games up in the West. The Yankees are the second favorite to win the World Series at +430, just behind the Los Angeles Dodgers (+420), according to Caesars Sportsbook. The Astros are the No. 3 choice at +700. The Dodgers visit the Braves, the fifth favorite at +1200, in an NL showdown as part of the 15-game MLB schedule for Friday night.

With a huge slate of games, there are tons of options for you to cash in on wagers, and if you combine your top MLB picks into a parlay, you can score big. New York is a -130 favorite on the money line in the latest Astros vs. Yankees odds from Caesars Sportsbook. Houston is a +110 underdog, while the Over/Under for total runs scored is eight. First pitch is set for 7:05 p.m. ET. (See up-to-date lines for every game on our MLB odds page.)

Before you make any MLB picks or parlays, be sure to see the predictions and betting advice from SportsLine's proven computer model.

The SportsLine Projection Model simulates every MLB game 10,000 times and it is off to a strong start to the 2022 season. It's on a 56-47 roll on top-rated MLB money-line picks through 11 weeks. Anybody who has followed it has seen profitable returns.

Now, the model has set its sights on the MLB schedule for Friday, June 24. Using its top picks for the day, the model has generated a four-leg parlay that would pay almost 13-1! The parlay doesn't start until 7:20 p.m. ET, giving you plenty of time to make your MLB picks.

We can tell you that one of the picks is Atlanta to cover the 1.5-run spread (-145) in the Dodgers vs. Braves matchup at 7:20 p.m. ET! The model has Atlanta winning the game outright in 54 percent of its simulations and covering 69 percent of the time. The model has three other picks, including two CONFIDENT money line plays on underdogs! You ABSOLUTELY need to see them before locking in any MLB picks of your own.

So which lines have value and can help you cash in BIG Friday night? And which underdogs are MUST-BACKS for a parlay with a payout of almost 13-1? ... Join SportsLine right now to find out which picks you should be all over on Friday, all from the model that is on a 56-47 roll on top-rated MLB money-line picks through 11 weeks!