MLB odds, lines, picks: Advanced computer model includes Mariners in parlay for April 21 that would pay more than 10-1

Texas is off to its worst start since 1987, losing nine of its first 11 games. The Rangers are riding a five-game losing streak heading into its matchup at Seattle on Thursday night. They have dropped the first two games of the series and have now scored three runs or fewer in each of their last four games. Seattle, meanwhile, has won five of its last six games, with the lone loss coming to Houston last Saturday. 

Seattle is a -130 money-line favorite in the latest Mariners vs. Rangers odds from Caesars Sportsbook, while Texas is a +110 underdog. First pitch at T-Mobile Park is set for 9:40 p.m. ET. The game is one of 10 on the MLB schedule on Thursday. (See up-to-date lines for every game on our MLB odds page.)

Before making any MLB picks or parlays, be sure to see the MLB predictions and betting advice from SportsLine's proven computer model.

The SportsLine Projection Model simulates every MLB game 10,000 times and it is off to a sizzling start to the 2022 season. It's on a 14-4 roll on top-rated MLB moneyline picks through two weeks, returning more than $800 for $100 players. Anyone following it has seen HUGE returns.

Now, the model has set its sights on the MLB schedule for Thursday, April 21. Using its top picks for the day, the model has generated a four-team parlay that would pay more than 10-1! The parlay doesn't start until 4:05 p.m. ET, giving you plenty of time to make your MLB picks!

We can tell you that one of the picks is the Mariners (-130) to beat the Rangers (9:40 p.m. ET). The model has three other picks, including a play on another small favorite! You ABSOLUTELY need to see them before locking in any MLB picks of your own.

So which small favorite is a MUST-BACK? And what other teams do you need to include in your parlay for a payout of 10-1? ... Join SportsLine right now to find out which picks you should be all over on Thursday, all from the model that is on a 14-4 roll on top-rated MLB money-line picks through two weeks!