MLB DFS, 2026: Top FanDuel, DraftKings picks, lineups, advice for Friday, April 10, from a daily Fantasy pro

Friday will feature 15 games, beginning at 2:20 p.m. ET, with the last first pitch set for 10:10 p.m. ET. Among the top options in the MLB DFS player pool include Tyler Glasnow, Shane Baz, Shohei Ohtani, Aaron Judge, Bobby Witt Jr., Kyle Tucker, Jose Ramirez, Byron Buxton, Christian Yelich, George Springer and Jackson Merrill. Among those on the injured list include Lourdes Gurriel Jr. (knee), Spencer Strider (oblique), Jackson Chourio (hand), Andrew Vaughn (hand), Anthony Volpe (shoulder), Seiya Suzuki (knee) and Hunter Greene (elbow).

Before making any MLB DFS picks on sites like DraftKings and FanDuel for this slate, you need to see what Mike McClure has to say.

McClure is a DFS professional with over $2 million in career winnings. He's also a predictive data engineer at SportsLine who uses a powerful prediction model that simulates every minute of every game 10,000 times, taking factors like matchups, statistical trends and injuries into account.

This allows him to find the best MLB DFS values and create optimal lineups that he shares only at SportsLine. They're a must-see for any MLB DFS player.

For Friday, one of McClure's top MLB DFS picks is New York Yankees outfielder Randal Grichuk ($2,400 DraftKings, $2,300 FanDuel). He's also building around Yankees infielder Amed Rosario ($2,500 DraftKings, $2,600 FanDuel). Last season, in six games, Rosario is hitting .250 with two home runs and five RBI. In 62 games a year ago, he batted .276 with 11 doubles, six homers and 23 RBI.

McClure is also targeting a player who could go off for massive numbers on Friday! This pick could be the difference between winning your tournaments and cash games or going home with nothing. You absolutely need to see who it is before locking in any lineups.

What are the top MLB DFS picks for Friday? ... Join SportsLine now to see DFS pro Mike McClure's top picks, stacks, and player pools for FanDuel and DraftKings, and cash in BIG on MLB DFS!