We've got another exciting SEC matchup on the schedule as the Mississippi State Bulldogs and the Ole Miss Rebels are set to tip at 9 p.m. ET on Wednesday at Humphrey Coliseum. Mississippi State is 17-8 overall and 10-2 at home, while Ole Miss is 19-6 overall and 3-5 on the road. Miss. State is favored by 6.5 points in the latest Mississippi State vs. Ole Miss odds, and the over/under is 141 points.

Before entering any Miss. State vs. Ole Miss picks, you'll want to see the NCAA Basketball predictions from the model at SportsLine.

The model simulates every Division I college basketball game 10,000 times. It enters Week 16 of the 2023-24 season on a 136-89 roll on all top-rated college basketball picks dating back to last season, returning nearly $2,500 for $100 players. It is also off to a sizzling 25-13 start on top-rated spread picks this season. Anyone following has seen huge returns.

The model has simulated Miss. State vs. Ole Miss 10,000 times and the results are in. We can tell you that the model is leaning Under, and it's also generated a point-spread pick that is hitting in well over 50% percent of simulations. 

So who wins Miss. State vs. Ole Miss? And which side of the spread is a must-back? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its college basketball picks. If you're already a member, see the picks below!