The No. 14 Ole Miss Rebels take on the Mississippi State Bulldogs in the 2022 Egg Bowl at 7 p.m. ET on Thanksgiving night. Ole Miss is favored by 2 points at Caesars Sportsbook, while the over/under is set at 6 (see up-to-date odds for every game this week on our college football odds page). 

Before making any Mississippi State vs. Ole Miss picks, you NEED to check out the college football predictions from the SportsLine Projection Model.

The SportsLine Projection Model simulates every FBS college football game 10,000 times. Over the past six-plus years, the proprietary computer model has generated a stunning profit of almost $3,000 for $100 players on its top-rated college football picks against the spread. Anyone who has followed it has seen HUGE returns.

The model knows Mississippi State is playing well on defense this season. The Bulldogs are yielding just 24.4 points per game and 351.7 total yards per game in 2022. That includes a top-five mark in the SEC in passing defense, giving up only 202.2 yards per game. Opponents are completing only 56.9% of passes against Mississippi State and averaging only 6.4 yards per attempt. The model also knows Ole Miss is dynamic on offense. The Rebels are No. 4 in the country in total offense, averaging more than 500 yards per game, and Ole Miss leads the SEC with 278.3 rushing yards per game. Lane Kiffin's team is averaging 5.8 yards per carry with 31 rushing touchdowns on the way to 35.3 points per game.

Now, it has set its sights on Mississippi State vs. Ole Miss. We can tell you the model is leaning Under the total, and it also says one side of the spread hits in more than 60% of simulations! You ABSOLUTELY need to see it before locking in any college football picks.

Who wins Mississippi State vs. Ole Miss? And which side of the spread hits in more than 60% of simulations? ... Join SportsLine right now to find out which side of the Mississippi State vs. Ole Miss spread you should be all over Thursday, all from the model on a roll on college football picks!