The Mississippi State Bulldogs take on the Memphis Tigers at 7:30 p.m. ET on Saturday at Davis Wade Stadium at Scott Field. The Bulldogs finished 7-6 with a disappointing loss to Texas Tech in the Liberty Bowl to end last season, while Memphis finished 6-6 and beat Mississippi State by two points early last year. Mississippi State quarterback Will Rogers returns to lead the offense after throwing for 4,739 yards and 36 touchdowns in 2021.

The Bulldogs are favored by 16 points in the latest Mississippi State vs. Memphis odds from Caesars Sportsbook, and the over-under is set at 57. Before you make any Memphis vs. Mississippi State picks, you'll want to see the college football predictions from the SportsLine Projection Model.

The SportsLine Projection Model simulates every FBS college football game 10,000 times. Over the past six-plus years, the proprietary computer model has generated a stunning profit of almost $3,600 for $100 players on its top-rated college football picks against the spread. It enters Week 1 of the 2022 college football season on a 45-32 run on all top-rated college football side picks that dates back to 2021. Anyone who has followed it has seen huge returns.

Now, it has simulated Mississippi State vs. Memphis 10,000 times and the results are in. We can tell you that the model is leaning Under, and it's also generated a point-spread pick that is hitting in over 60 percent of simulations. You absolutely need to see it before locking in your own picks.

Who wins Mississippi State vs. Memphis? And which side of the spread is a must-back? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its college football picks ... If you're already a member, see the picks below!