Minnesota vs. Penn State prediction, odds, line: Advanced college football model reveals picks for Saturday night's Big Ten Conference matchup

Teams looking to rebound from big losses a week ago clash when the Minnesota Golden Gophers battle the 16th-ranked Penn State Nittany Lions in a Big Ten crossover matchup on Saturday. The Gophers (4-2, 1-2) have lost two in a row, including a 26-14 decision at Illinois last week. The Nittany Lions (5-1, 2-1), meanwhile, were pounded 41-17 at then-No. 10 Michigan. Penn State holds a 9-6 edge in the series, although Minnesota won the last meeting 31-26 in 2019.

Kickoff from Beaver Stadium in University Park, Pa., is set for 7:30 p.m. ET. Penn State is a 5-point favorite in the latest Minnesota vs. Penn State odds from Caesars Sportsbook, while the over/under for total points scored is 43. (See up-to-date odds for every game this week on our college football odds page.) 

Before you make any Minnesota vs. Penn State picks or college football predictions, you NEED to see the predictions from the SportsLine Projection Model.

The SportsLine Projection Model simulates every FBS college football game 10,000 times. Over the past six-plus years, the proprietary computer model has generated a stunning profit of almost $3,000 for $100 players on its top-rated college football picks against the spread. Anyone who has followed it has seen HUGE returns!

The model knows senior quarterback Sean Clifford leads the Nittany Lions offense. He has completed 92 of 156 passes (59 percent) for 1,150 yards and nine touchdowns, while throwing just two interceptions. He has also rushed 32 times for 141 yards (4.4 average) and four scores. In a 35-31 season-opening win at Purdue on Sept. 1, he completed 20 of 37 passes for 282 yards (54.1 percent) and four touchdowns. He was picked off once.

The model also knows the Golden Gophers have a solid offense, even without senior quarterback Tanner Morgan, who is questionable due to a head injury he suffered in the loss to Illinois. Whether or not he plays, Minnesota has other weapons, including senior running back Mohamed Ibrahim. Ibrahim leads the team with 104 carries for 694 yards (6.7 average) and nine touchdowns. He has scored at least one touchdown in all five games he has played, including three against Colorado on Sept. 17. In that game, he carried 23 times for 202 yards (8.8 average).

Now, the model has set its sights on Minnesota vs. Penn State. We can tell you it is leaning Over the total, and it also says one side of the spread hits more than 50% of the time! You ABSOLUTELY need to see it before locking in any college football picks.

Who wins Minnesota vs. Penn State? And which side of the spread hits more than 50% of the time? ... Join SportsLine right now to find out which side of the Minnesota vs. Penn State spread you should be all over Saturday, all from the model on a roll on college football picks!