The sixth-ranked Michigan Wolverines take on the Penn State Nittany Lions in a key Big Ten Conference East Division matchup at noon ET on Saturday. Michigan is favored by 1.5 points at Caesars Sportsbook, while the Over-Under is set at 48.5 (see up-to-date odds for every game this week on our college football odds page). 

Before making any Michigan vs. Penn State picks, you NEED to check out the college football predictions from the SportsLine Projection Model.

The SportsLine Projection Model simulates every FBS college football game 10,000 times. Over the past five-plus years, the proprietary computer model has generated a stunning profit of almost $3,500 for $100 players on its top-rated college football picks against the spread. It also enters Week 11 of the 2021 season on a 31-20 run on all top-rated college football side picks. Anyone who has followed it has seen HUGE returns.

The model knows the Wolverines are still in the mix for the division championship and will probably need to win out to catch Ohio State. Leading the offense is junior quarterback Cade McNamara, who has completed 62.5 percent of his passes on 130 of 208 passing for 1,666 yards and nine touchdowns. He has been picked off twice, but has a rating of 142.1.McNamara has also rushed for one score. With McNamara behind center, the Wolverines have scored points on 53.1 percent of their drives. McNamara has directed 113 series over the past two seasons, leading the team to 60 scores.  

The model also knows the Nittany Lions have a veteran quarterback in senior Sean Clifford. Clifford has completed 199 of 311 passes (64 percent) for 2,371 yards and 16 touchdowns. He has been intercepted six times and has a rating of 141.1. Clifford has also rushed for a pair of touchdowns. He has thrown for more than 350 yards in each of the past two games, including a 27-for-47 performance for 363 yards and three touchdowns at Maryland last week.

Now, it has set its sights on Michigan vs. Penn State. We can tell you the model is leaning Over on the total, and it also says one side of the spread hits in well over 60 percent of the time! You ABSOLUTELY need to see it before locking in any college football picks.

Who wins Michigan vs. Penn State? And which side of the spread hits well over 60 percent of the time? ... Join SportsLine right now to find out which side of the Michigan vs. Penn State spread you should be all over Saturday, all from the model on a roll on college football picks!