Michigan vs. Michigan State odds, prediction: 2026 Big Ten college basketball picks from proven model

One of the top rivalries in college basketball unfolds on Sunday when the No. 3 Michigan Wolverines host the No. 8 Michigan State Spartans in the final regular season Big Ten game for both squads. Michigan State is 25-5 (15-4 Big Ten), while Michigan is 28-2 (18-1 Big Ten). 

Tipoff from the Crisler Center is set for 4:30 p.m. ET on CBS and Paramount+. The Wolverines are 9.5-point favorites in the latest Michigan vs. Michigan State odds, while the over/under is 151.5.

Before making any Michigan State vs. Michigan picks, check out the college basketball predictions from the SportsLine Projection Model.

The SportsLine Projection Model simulates every college basketball game 10,000 times. It entered Week 18 on a sizzling 11-1 run on top-ranked over/under picks dating back to last year, and is on an 23-17 run on top-rated CBB side picks. Anyone following could have seen HUGE returns!

The model has simulated Michigan State vs. Michigan 10,000 times and the results are in. The model is leaning Under, and it also says one side of the spread hits in well over 50% of simulations!

So who wins Michigan State vs. Michigan, and which side of the spread hits well over 50% of the time? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has simulated this matchup 10,000 times!