The No. 9 Michigan Wolverines will begin their title defense when they host the Fresno State Bulldogs on Saturday night. Michigan won the national championship in a 34-13 final against Washington before head coach Jim Harbaugh left for the Chargers. He was replaced by Sherrone Moore, who will make his full-time debut against a Fresno State team that went 9-4 last season.  

Kickoff is scheduled for 7:30 p.m. ET on Saturday at Michigan Stadium. Michigan is favored by 21.5 points in the latest Michigan vs. Fresno State odds, while the over/under is 45.5 points, per SportsLine consensus. Before entering any Fresno State vs. Michigan picks, you'll want to see the college football predictions from the model at SportsLine.

The model simulates every FBS college football game 10,000 times. Since its inception, it has generated a profit of well over $2,000 for $100 players on its top-rated college football picks against the spread. It is also coming off a profitable 13-9 season on top-rated spread picks. Anyone who has followed it has seen strong returns.

The model has simulated Michigan vs. Fresno State 10,000 times and the results are in. We can tell you that the model is leaning Over, and it's also generated a point-spread pick that hits in over 50% of simulations. You can only see the pick at SportsLine.

So who wins Michigan vs. Fresno State? And which side of the spread hits over 50% of the time? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its college football picks.