Michigan State vs. Nebraska odds, line, spread: Proven model reveals college basketball picks, predictions for Jan. 5, 2022

A Big Ten battle is on tap between the No. 10 Michigan State Spartans and the Nebraska Cornhuskers at 7 p.m. ET on Wednesday at the Jack Breslin Student Events Center. The Spartans are 12-2 overall and 6-0 at home, while Nebraska is 6-8 overall and 0-2 on the road. Michigan State is ranked first in the Big Ten; Nebraska is ranked 13th. 

The Spartans are favored by 16 points in the latest Michigan State vs. Nebraska odds from Caesars Sportsbook, while the over-under is set at 150.5. Before you make any Nebraska vs. Michigan State picks and predictions, you'll want to see what the SportsLine Projection Model is saying.

The SportsLine Projection Model simulates every Division I college basketball game 10,000 times. Over the past five-plus years, the proprietary computer model has generated an impressive profit of almost $2,200 for $100 players on its top-rated college basketball picks against the spread. Anyone who has followed it has seen huge returns.

Now, it has simulated Michigan State vs. Nebraska 10,000 times and the results are in. We can tell you that the model is leaning Under, and it's also generated a point-spread pick that is hitting in well over 50 percent of simulations. You absolutely need to see it before locking in your own picks.

So who wins Michigan State vs. Nebraska? And which side of the spread is a must-back? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its college basketball picks.