The No. 7 Michigan State Spartans (23-12) and the No. 2 Duke Blue Devils (29-6) collide in the second round of the 2022 NCAA Tournament on Sunday afternoon at 5:15 p.m. ET. Duke is favored by 6.5-points at Caesars Sportsbook, while the Over-Under is set at 146 (see up-to-date odds for every game this week on our college basketball odds page). 

Before making any Michigan State vs. Duke picks, you NEED to check out the college basketball predictions from the SportsLine Projection Model.

The SportsLine Projection Model simulates every Division I college basketball game 10,000 times. Over the past five-plus years, the proprietary computer model has generated an impressive profit of almost $1,500 for $100 players on its top-rated college basketball picks against the spread. Anyone who has followed it has seen HUGE returns.

The model knows Duke freshman forward Paolo Banchero averages 17 points and 7.9 rebounds per game. Banchero has been great on the boards, snagging double-digit rebounds in 11 games. The Washington native had a solid outing in the first-round win. He tallied 17 points, 10 rebounds, four assists, and two blocks. 

The model also knows Michigan State senior forward Gabe Brown is leading the team with 11.4 points, 3.9 rebounds, while shooting 37 percent from downtown. The Michigan native has scored in double figures in seven of his last eight games. In his last matchup, Brown dropped 12 points, three assists, and knocked down three 3-pointers. 

Now, it has set its sights on Michigan State vs. Duke. We can tell you the model is leaning Over the total, and it also says one side of the spread hits in 60 percent of simulations! You ABSOLUTELY need to see it before locking in any college basketball picks.

Who wins Michigan State vs. Duke? And which side of the spread hits in 60 percent of simulations? ... Join SportsLine right now to find out which side of Michigan State vs. Duke spread you should be all over Sunday, all from the model on a roll on college basketball picks!