An American Conference matchup features Memphis (13-8) going on the road to take No. 6 Houston (20-3) on Saturday afternoon at 3:30 p.m. ET. Memphis beat Tulane 80-69 in its last game to win its fourth straight contest. On Feb. 9, Houston was upset by SMU 85-83. This loss snapped Houston's 12-game winning streak. Houston is favored by 9.5 points and the over-under for total points is set at 141.5 at Caesars Sportsbook.

Before making any Memphis vs. Houston picks, you NEED to check out the college basketball predictions from the SportsLine Projection Model.  

The SportsLine Projection Model simulates every Division I college basketball game 10,000 times. Over the past five-plus years, the proprietary computer model has generated an impressive profit of over $2,300 for $100 players on its top-rated college basketball picks against the spread. Anyone who has followed it has seen HUGE returns.

The model knows Houston senior guard Kyler Edwards is averaging 14 points, 5.8 rebounds and 2.7 assists per game. Edwards has scored at least 15 points in six of the last 10 games he's played in. During this stretch, the Texas native has hit at least four 3-pointers in five of those matchups. In the loss to SMU, Edwards had 17 points, four rebounds and four assists. 

The model also knows Memphis freshman center Jalen Duren is logging 11.1 points, 7.8 rebounds and is shooting a team-high 63 percent from the field. The Pennsylvania native has recorded back-to-back double-doubles for the Tigers. In the win over Tulane, Duren finished with 15 points, 12 rebounds, and shot 6-for-7 from the field. 

Now, it has set its sights on Memphis vs. Houston. We can tell you the model is leaning Under the total and it also says one side of the spread hits in almost 70 percent of simulations! You ABSOLUTELY need to see it before locking in any college basketball picks.

Who wins Memphis vs. Houston? And which side of the spread hits in almost 70 percent of simulations? ... Join SportsLine right now to find out which side of Memphis vs. Houston spread you should be all over Saturday, all from the model on a roll on college basketball picks!